Bactfast® - Pathogen Stack for Bacterial Identification

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Bactfast®

Bactfast® is a CE-IVDR–certified pan-bacterial identification solution built on Credence Genomics’ pathogen detection platform, a proprietary technology stack combining long-read sequencing, targeted metagenomics, and machine learning.

Designed for rapid, culture-independent diagnostics, Bactfast® enables comprehensive bacterial detection and predictive antimicrobial resistance insights in less than 24 hours, supporting confident clinical decision-making when it matters most.

Integrated sequencing, machine learning, and advanced modelling — delivering precise, reproducible pathogen insights.

Bactfast® uses 16S rRNA gene–based targeted metagenomic sequencing (tmNGS) to directly analyse bacterial DNA from clinical samples. Advanced bioinformatics and machine-learning algorithms ensure precise organism identification and resistance gene detection.

Coverage: 22,000+ bacterial organisms, includes genus and species-level identification

Regulatory Status: CE-IVDR certified

Why Bactfast®?

In critical infections, time and accuracy save lives. Traditional culture-based methods are slow, limited, and often inconclusive, especially in patients who are already on antibiotics or infected with fastidious or unculturable organisms.

Agnostic Pathogen Detection

No prior assumptions required.

Culture-independent testing

Detects both culturable and unculturable bacteria.

Rapid turnaround time

Actionable results in <24 hours.

High accuracy and sensitivity

Up to 99% accuracy, operator-independent.

Comprehensive coverage

Entire known bacterial spectrum in one test.

Clinical Applications​

Bactfast® is especially valuable in high-acuity and diagnostically challenging scenarios, including:

Non-resolving post-surgical infections

Prosthetic joint and valve infections

Deep tissue and sterile site infections

Sepsis and septic shock

Culture-negative infections

Chronic or recurrent infections

Immunocompromised patients

Post-transplant infections

Meningitis

Aligned with international guidelines

International guidelines increasingly recommend sequencing-based approaches in:

Culture-negative infections

Immunocompromised patients

Recurrent or unexplained infections

The Challenge

The Limitations of Traditional Bacterial Diagnostics

Slow Culture Turnaround

Delays in obtaining results can postpone targeted treatment, increasing the risk of complications in critical patients.

Culture-Negative Infections

When infections go undetected by traditional methods, clinicians face diagnostic uncertainty that can compromise timely care.

Limited Pathogen Scope

Tests that miss less common or slow-growing organisms may result in incomplete diagnoses, hindering effective treatment decisions.

Contamination ambiguity

Tests that miss less common or slow-growing organisms may result in incomplete diagnoses, hindering effective treatment decisions.

Clinical Applications

Bactfast® is especially valuable in high-acuity and diagnostically challenging scenarios, including:

Sepsis and septic shock
Culture-negative infections
Chronic or recurrent infections
Non-resolving post-surgical infections
Prosthetic joint and valve infections
Deep tissue and sterile site infections
Immunocompromised patients
Post-transplant infections
Meningitis

Aligned with international guidelines

International guidelines increasingly recommend sequencing-based approaches in:

Culture-negative infections
Immunocompromised patients
Recurrent or unexplained infections

The SOLUTION

How Bactfast® Delivers Diagnostic Clarity

Bactfast® uses next-generation sequencing and proprietary bioinformatics to rapidly identify bacterial pathogens with high specificity. Designed for complex and chronic cases, it delivers a complete diagnostic picture when traditional testing is inconclusive.

Metric
Bactfast®
Bacterial Culture
Filmarray and Bacterial PCR Panels
Insight
Detection Approach
Targeted metagenomic sequencing (16S rRNA)
Growth-based
Targeted amplification
Broad detection without organism pre-selection
Organism Coverage
22,000+ bacterial species
Limited (culturable organisms)
Limited (panel-restricted)
Comprehensive bacterial spectrum in a single test
Culture-Independent Detection
Yes
No
Yes (with an exception in some molecular modalities where positive culture sample is required)
Detects fastidious and unculturable bacteria
Detection in Culture-Negative Infections
High
None
Variable
Identifies infections missed by culture
Mixed/Polymicrobial infections
Clearly detected
Often missed
Partially detected
Resolves complex polymicrobial infections
Species-Level Resolution
High (genus & species)
Variable
Variable
Enables confident clinical interpretation
Turnaround Time
<24 hours
2–5 days
12–72 hours
Faster results enable earlier targeted therapy
Sensitivity in Invasive Disease
High
Variable
Moderate
Improved detection in low bacterial burden

Learn more about our pathogen detection stack and platform capabilities.

Faster, Broader, More Accurate Diagnostics

Bactfast® empowers clinicians with actionable insights by detecting a wide spectrum of bacterial pathogens—even those missed by traditional methods. With faster turnaround times and high concordance to culture-positive results, it provides reliable information that supports confident, timely treatment decisions. By combining broad coverage with precision analysis, Bactfast® transforms complex microbial data into clarity at the point of care.

Accuracy of Pathogen Detection

Sensitivity
0%
Sensitivity - (Considering Clinical Compatibility)
0%
Specificity
0%
Specificity - (Considering Clinical Compatibility)
0%

Read More About Our Research.

Delivering Clear Results

Broad Pathogen Coverage

Bactfast® delivers a complete diagnostic picture when traditional culture and targeted PCR panels may fall short.

Predictive Intelligence

Culture-independent detection helps identify pathogens sooner to support earlier, more confident clinical decisions.

Actionable Clinical Insights

Predictive intelligence adds clinical context that strengthens decision-making for critical care and complex infections.

Credence Genomics
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