Rapid Bacterial Identification Test with Bactfast®

Bactfast® is a CE-IVDR–certified bacterial identification test and pan-bacterial identification solution powered by AIoS™, Credence Genomics’ proprietary Pathogen Stacks technology combining long-read sequencing, targeted metagenomics, and machine learning. Designed for rapid, culture-independent diagnostics, Bactfast® enables comprehensive bacterial detection and MMR™-powered predictive antimicrobial resistance insights in less than 24 hours—supporting confident clinical decision-making in sepsis and other critical infections when it matters most.

Comprehensive Bacterial Detection

Bactfast® is a CE-IVDR–certified pan-bacterial identification solution powered by AIoS™, Credence Genomics’ proprietary Pathogen Stacks technology combining long-read sequencing, targeted metagenomics, and machine learning.

Designed for rapid, culture-independent diagnostics, Bactfast® enables comprehensive bacterial detection and MMR™-powered predictive antimicrobial resistance insights in less than 24 hours — supporting confident clinical decision-making in sepsis and other critical infections, when it matters most.

Integrated sequencing, machine learning, and advanced modelling — delivering precise, reproducible pathogen insights.

Bactfast® uses 16S rRNA gene–based targeted metagenomic sequencing (tmNGS) to directly analyse bacterial DNA from clinical samples. Advanced bioinformatics and machine-learning algorithms ensure precise organism identification and resistance gene detection.

Coverage: 22,000+ bacterial organisms, includes genus and species-level identification

Regulatory Status: CE-IVDR certified

GLOBAL REACH

  • 13+ Countries
  • 62+ Hospitals & Labs
  • 250K+ Hospital Beds
  • 1,500+ Pathogens Detected

Clinical Applications​

Bactfast® is commonly used in high-risk and diagnostically complex scenarios, and is especially valuable when traditional bacterial culture or PCR testing is negative, delayed, or inconclusive. Those scenarios include:

Sepsis and septic shock

Culture-negative infections

Polymicrobial infections

Fastidious and anaerobic infections

Non-resolving infections

Immunocompromised patients

Post-surgical and prosthetic infections

Neurological infections (meningitis, brain abscess)

Endocarditis

Why Bactfast®?

In critical infections, time and accuracy save lives. Traditional culture-based methods are slow, limited, and often inconclusive, especially in patients who are already on antibiotics or infected with fastidious or unculturable organisms.

Agnostic Pathogen Detection

No prior assumptions required.

Culture-independent testing

Detects both culturable and unculturable bacteria.

Rapid turnaround time

Actionable results in <24 hours.

High accuracy and sensitivity

Up to 99% accuracy, operator-independent.

Comprehensive coverage

Entire known bacterial spectrum in one test.

Clinical Applications​

Bactfast® is especially valuable in high-acuity and diagnostically challenging scenarios, including:

Non-resolving post-surgical infections

Prosthetic joint and valve infections

Deep tissue and sterile site infections

Sepsis and septic shock

Culture-negative infections

Chronic or recurrent infections

Immunocompromised patients

Post-transplant infections

Meningitis

Aligned with international guidelines

International guidelines increasingly recommend sequencing-based approaches in:

Culture-negative infections

Immunocompromised patients

Recurrent or unexplained infections

The Challenge

The Limitations of Traditional Bacterial Diagnostics

Slow Culture Turnaround

Delays of 3-7 days in obtaining results can postpone targeted treatment, increasing the risk of complications in critical patients.

Culture-Negative Sepsis

In 10-30% of sepsis cases, cultures return negative despite clear clinical infection, leaving diagnostic uncertainty that can compromise timely care.

Polymicrobial & Anaerobic Blind Spots

Mixed infections and anaerobic organisms are frequently underdiagnosed or missed entirely by conventional culture methods.

Narrow Pathogen Scope

PCR panels and film array cover a limited set of organisms, making them unsuitable as a true agnostic diagnostic test.

Clinical Applications

Bactfast® is especially valuable in high-acuity and diagnostically challenging scenarios, including:

Sepsis and septic shock
Culture-negative infections
Chronic or recurrent infections
Non-resolving post-surgical infections
Prosthetic joint and valve infections
Deep tissue and sterile site infections
Immunocompromised patients
Post-transplant infections
Meningitis

Aligned with international guidelines

International guidelines increasingly recommend sequencing-based approaches in:

Culture-negative infections
Immunocompromised patients
Recurrent or unexplained infections

The SOLUTION

How Bactfast® Delivers Diagnostic Clarity

Bactfast® uses next-generation sequencing and proprietary bioinformatics to rapidly identify bacterial pathogens with high specificity. Designed for complex and chronic cases, it delivers a complete diagnostic picture when traditional testing is inconclusive.

Metric
Bactfast®
Bacterial Culture
Bacterial PCR Panels
Insight
Detection Approach
Targeted metagenomic sequencing (16S rRNA)
Growth-based
Targeted amplification
Unbiased sequencing avoids organism pre-selection
Organism Coverage
22,000+ bacterial species
Limited (common, culturable bacteria)
Limited (panel-restricted)
Broad-spectrum detection in a single test
Culture-Independent Detection
Yes
No
Yes
Effective even after antibiotic therapy
Detection in Culture-Negative Infections
High (94.1% sensitivity)
None
Variable
Identifies infections missed by culture
Mixed/co-infections
Clearly detected
Often missed
Partially detected
Resolves complex polymicrobial infections
Anaerobic organism detection
Yes
Requires specialized protocol; often missed
Variable
Detected in same assay as aerobes
Turnaround Time
<24 hours
3–7 days
12–24 hours
Faster results enable earlier intervention
Resistance insight
MMR™ included
Requires separate susceptibility testing (+24–48h)
Not included
Data-driven therapy decisions, same report
Metric
Bactfast®
Bacterial Culture
Bacterial PCR Panels
Insight
Detection Approach
Targeted metagenomic sequencing (16S rRNA)
Growth-based
Targeted amplification
Broad detection without organism pre-selection
Organism Coverage
22,000+ bacterial species
Limited (culturable organisms)
Limited (panel-restricted)
Comprehensive bacterial spectrum in a single test
Culture-Independent Detection
Yes
No
Yes (with an exception in some molecular modalities where positive culture sample is required)
Detects fastidious and unculturable bacteria
Detection in Culture-Negative Infections
High
None
Variable
Identifies infections missed by culture
Mixed/Polymicrobial infections
Clearly detected
Often missed
Partially detected
Resolves complex polymicrobial infections
Species-Level Resolution
High (genus & species)
Variable
Variable
Enables confident clinical interpretation
Turnaround Time
<24 hours
2–5 days
12–72 hours
Faster results enable earlier targeted therapy
Sensitivity in Invasive Disease
High
Variable
Moderate
Improved detection in low bacterial burden

Learn more about our pathogen detection stack and platform capabilities.

Faster, Broader, More Accurate Diagnostics

Bactfast® empowers clinicians with actionable insights by detecting a wide spectrum of bacterial pathogens—even those missed by traditional methods. With faster turnaround times and high concordance to culture-positive results, it provides reliable information that supports confident, timely treatment decisions. By combining broad coverage with precision analysis, Bactfast® transforms complex microbial data into clarity at the point of care.

ACCURACY OF BACTERIAL DETECTION

Sensitivity
0%
Specificity
0%
Sensitivity - (With clinical correlation)
0%
Bacterial Coverage 22,000+
0%

Read More About Our Research.

Delivering Clear Results

Broad Pathogen Coverage

Bactfast® delivers a complete diagnostic picture when traditional culture and targeted PCR panels may fall short.

Predictive Intelligence

Culture-independent detection helps identify pathogens sooner to support earlier, more confident clinical decisions.

Actionable Clinical Insights

Predictive intelligence adds clinical context that strengthens decision-making for critical care and complex infections.

Credence Genomics
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